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Store the unopened lyophilized vial at 20C for long-term storage (24 months)
Interestingly, inhibiting HDACs increases RB1 expression in MDSCs, halting their progression into immunosuppressive subsets and promoting their differentiation into cell types that enhance immune activity [106]
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This conversation should occur at tirzepatide initiation and revisited during dose escalations, as manufacturer guidance recommends backup contraception during these periods
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